Endoscopic nipple-sparing mastectomy (E-NSM) is a minimally invasive breast surgery technique for both prophylactic mastectomies and the treatment of breast cancer. Using one small incision located off the breast, the GelPOINT Mini advanced access platform facilitates E-NSM by enhancing visualization and improving ergonomics while allowing for transillumination of the mastectomy flap and real-time tactile feedback at the patient’s bedside.
DOWNLOAD CLINICAL EVIDENCE OVERVIEWCompared with the open approach, E-NSM has been shown to provide many patient benefits:
Better Cosmetic Outcomes1
Less PostOperative Pain2
Higher Patient Satisfaction and Psychological Well-Being1
Potential Reduction of Complications1
The E-NSM course is designed to provide surgeons with a comprehensive understanding of the E-NSM technique.
The course includes the following:
Contact us for more information about E-NSM and course availability in your region.
E-NSM COURSE INTEREST FORME-NSM: A Modern Approach for the Minimally Invasive Breast Surgeon
Wednesday, 21 Oct. 2026 | 19:30–20:30 CEST
Join our panel of experts for an engaging webinar on E-NSM (endoscopic nipple-sparing mastectomy). Learn more about this minimally invasive technique through step-by-step procedural footage and an in-depth review of the most up-to-date clinical evidence, and discover how to implement E-NSM into your practice. Live Q&A to follow.
Lidia Blay
Germans Trias i Pujol
University Hospital, Spain
Femke Delporte
Sint-Lucas General
Hospital Brugge, Belgium
Giada Pozzi
Candiolo Cancer
Institute, Italy
E-NSM: The Future of Breast Surgery Is Endoscopic
Endoscopic nipple-sparing mastectomy (E-NSM) is shaping the future of minimally invasive breast surgery. Join our global panel of surgeons to discover why E-NSM is a growing part of their practice. The panel will share experiences from initial U.S. cases, procedural footage, the benefits of the technique, and insights from current clinical evidence. Come see how E-NSM is taking breast surgery to the next level!
John Davis, MD
Comprehensive Breast
Center of Arizona, U.S.
Richard Ehlers II, MD
UT MD Anderson
Cancer Center, U.S.
Paula Escobar, MD
Cleveland Clinic, U.S.
Robert Milligan, MD
Queen Elizabeth
Hospital, U.K.
Giada Pozzi, MD
Candiolo Cancer
Institute, Italy
1. Carroll A, Robles C, Lai HW, et al. Oncological, surgical, and cosmetic outcomes of endoscopic versus conventional nipple-sparing mastectomy: meta-analysis. BJS Open. 2025;9(3):zraf011. doi:10.1093/bjsopen/zraf011
This review was funded by Applied Medical. No author has received any specific compensation for their work.
2. Lai HW, Chen DR, Liu LC, et al. Robotic Versus Conventional or Endoscopic-assisted Nipple-sparing Mastectomy and Immediate Prosthesis Breast Reconstruction in the Management of Breast Cancer: A Prospectively Designed Multicenter Trial Comparing Clinical Outcomes, Medical Cost, and Patient-reported Outcomes (RCENSM-P). Ann Surg. 2024;279(1):138-146. doi:10.1097/SLA.0000000000005924
